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123webguru, Boston's sick and infirm may soon have a new treatment tool at their disposal: one of the world's fastest supercomputers. By Mark Baard.

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Supercomputer for Dodgy Tickers

BOSTON -- Doctors here in Beantown may soon turn to one of the world's fastest supercomputers as an aid to fixing bum tickers and removing formerly inoperable tumors.

A new IBM BlueGene supercomputer, recently installed at Boston University, could give surgeons real-time, 3-D visualizations of patients' internal organs as they implant lifesaving devices or direct robotic instruments through tricky procedures, scientists said.

Rather than poking around in a patient while looking at a two-dimensional fluoroscopic image, implant doctors could work with a detailed, 3-D picture of organs and tissues produced by the supercomputer.

Even the fastest desktops are not up to the task. Only the latest generation of supercomputers is fast enough to take the flood of data from a CT scan and turn it into a live 3-D model of patients' insides.

"The value is the real-time capability," said BU professor of biomedical engineering Solomon Eisenberg, who is working with doctors at Brigham and Women's Hospital (Harvard Medical School's teaching hospital) on the 3-D visualization of patients' internal anatomies and implant devices.

"That's the holy grail piece: to have computational aspect happen fast enough to inform what you're doing next, when you are in the middle of doing a lot of things," he added.

BU's supercomputer has 2,048 IBM BlueGene/L processors, making the university one of the fastest supercomputer sites on the planet. It is ranked 59 in a recent survey of the world's top 500 supercomputers.

The BU supercomputer is not much to look at, however. It is a rack of tightly packed computer nodes about 6-and-one-half feet high. Two miles of gigabit ethernet cable beneath a raised floor connect BU's supercomputer to the outside world and two Linux servers, which manage the computational tasks submitted by researchers. A giant cooling system, the equivalent of 10 large home air-conditioning units, keeps the supercomputer from overheating.

"If the stack was any denser, we couldn't get rid of the heat," said Glen Bresnahan, director of the Scientific Computing and Visualization Group at BU.

Scientists at BU, Brigham and Women's Hospital and the medical technology company Guidant have been using BU's Deep Vision Display Wall to see if the computer can predict how much electricity is the right amount for an implantable defibrillator to zap a failing heart back into normal rhythm. (An implantable defibrillator is a tiny version of the carts and paddles often seen wielded by TV doctors to resuscitate patients.)

To adjust the settings of one of the tiny devices, implant doctors throw the heart into rapid uncoordinated contractions (a state called fibrillation), and then use the defibrillator to shock the organ back into rhythm.

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The intentional fibrillation ensures the implantable defibrillator provides enough of a shock to save the patient -- but doesn't use too much energy.

"You don't want to fry the heart," said Solomon Eisenberg, professor of biomedical engineering at BU. The only way to get the setting right is by trial and error, said Eisenberg, "to fibrillate and defibrillate."

Real-time 3-D visualizations running on the BU supercomputer could simulate the electrical fields inside a patient, which are created by the defibrillator's electrodes, Eisenberg believes.

The anatomy of each cardiac patient is unique: the position and shape of the heart, and the thickness of ventrical walls, for example, all help determine how a defibrillator shock will affect the heart.

"These are things that are not understood by looking at a person on the outside," said Eisenberg. "It's not related to how obese a person is, or how old."

BU plans to share about a third of its supercomputers' processing time with collaborators at Harvard and Tufts Universities, as well as other research institutions. The collaborators will be able to submit their applications and data to the supercomputer through the Internet2 high-speed research network.

BU's astronomy department will also use the supercomputer in an attempt to more accurately model and predict space weather events to protect the lives of astronauts in orbit and interplanetary space.

News Source
http://www.wired.com


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